Figure 7

Correlation of mRNA and protein changes between LS and PC T. brucei. ( A ) Scatter plot comparing RNA (x-axis) and protein (y-axis) change in log₂ between LS/PC. The colour of the circles change from red to green based on the correlation. The dashed lines indicate difference in fold-change ≤ 4 fold between RNA and protein. Spearman’s rank correlation rho=0.61 (p-value< 2.2E^-16) and Pearson’s product moment correlation is 0.74 (p-value < 2.2E^-16). The dotted lines indicate difference in fold-change ≤ 2 fold between RNA and protein. Spearman’s rank correlation rho=0.8339 (p-value< 2.2E^-16) and Pearson’s product moment correlation is 0.9 (p-value < 2.2E^-16). (B) Correlation and variability of mRNA and protein abundance changes during development based on the first two Principal components (PC).