Figure 6
From: Hepatitis B viral core protein disrupts human host gene expression by binding to promoter regions
Effects of HBV core protein binding to host gene promoters. Relative luciferase activity was measured in cells co-transfected with one of six tumor pathogenesis-associated genes and the HBc gene. The pGL3-basic plasmid was used as the negative control. The vertical axis represents the relative proportion of luciferase activity of (cells co-transfected with HBc expression vector)/(cells transfected without HBc expression vector). Data are expressed as mean ± SD, *p < 0.05. Basic-P, pGL3-basic vectors; HRAS-P, NTRK2-P, PDGFA-P, IGF1R-P, SRC-P and P53-P represent the pGL3-basic-constructed plasmids for the promoters of HRAS, NTRK2, PDGFA, IGF1R, SRC and P53 genes, respectively