Expression of genes associated with EIs. We compared expression levels for genes with TSS at different regions. Expression values are RPKM (read per kb per million reads) for lung fibroblast IMR90 . A) boxplot of expression level of genes with TSS 1) overlapping EIs; 2) overlapping LOCKs but not EIs; and 3) not overlapping EIs. B) Relationship between H3K36me3/H3K27me3 and expression of EI associated genes.