Table 4 Top 10 GO terms of genes associated with EIs
GO terms | % of genes | Fold en. | FDR |
|---|---|---|---|
Biological processes | |||
nervous system development | 12.6 | 2.2 | 9E-11 |
developmental process | 25.5 | 1.6 | 4E-09 |
system development | 20.5 | 1.7 | 4E-09 |
anatomical structure development | 21.5 | 1.6 | 1E-08 |
multicellular organismal development | 23.4 | 1.6 | 2E-08 |
cell adhesion | 8.7 | 2.4 | 8E-08 |
biological adhesion | 8.7 | 2.4 | 8E-08 |
cell differentiation | 15.2 | 1.8 | 4E-07 |
cell development | 8.0 | 2.4 | 4E-07 |
multicellular organismal process | 31.1 | 1.4 | 4E-07 |
Cellular compartment | |||
plasma membrane part | 21.1 | 1.9 | 4E-14 |
plasma membrane | 30.3 | 1.6 | 1E-12 |
membrane part | 44.2 | 1.3 | 1E-09 |
integral to plasma membrane | 12.6 | 2.1 | 3E-09 |
intrinsic to plasma membrane | 12.7 | 2.1 | 5E-09 |
membrane | 47.0 | 1.3 | 2E-08 |
intrinsic to membrane | 37.3 | 1.4 | 2E-07 |
integral to membrane | 35.9 | 1.4 | 1E-06 |
synapse | 5.3 | 3.0 | 2E-06 |
extracellular region | 16.7 | 1.7 | 6E-06 |
Molecular function | |||
calcium ion binding | 9.7 | 2.1 | 4E-06 |
gated channel activity | 4.5 | 2.9 | 9E-05 |
molecular transducer activity | 17.5 | 1.5 | 6E-04 |
signal transducer activity | 17.5 | 1.5 | 6E-04 |
substrate specific channel activity | 5.1 | 2.5 | 6E-04 |
ion channel activity | 4.9 | 2.5 | 8E-04 |
channel activity | 5.1 | 2.4 | 1E-03 |
passive transmembrane transporter activity | 5.1 | 2.4 | 1E-03 |
cation channel activity | 3.9 | 2.8 | 2E-03 |
ligand-gated channel activity | 2.3 | 3.6 | 1E-02 |