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Table 3 Accessory regions identified among S. pneumoniae isolates

From: Comparative phylogenomics of Streptococcus pneumoniae isolated from invasive disease and nasopharyngeal carriage from West Africans

Accessory Region

TIGR4 locus

Gene annotation

AR1

SP0482

hypothetical protein

 

SP0483

ABC transporter, ATP-binding protein

 

SP0484

hypothetical protein

AR2

SP1050

transcriptional regulator, putative

 

SP1051

hypothetical protein

 

SP1052

phosphoesterase, putative

AR3

SP1062

ABC transporter, ATP-binding protein

 

SP1063

ABC-2 transporter, permease protein, putative

 

SP1064

transposase, IS200 family

AR4

SP1129

integrase/recombinase, phage integrase family

 

SP1130

transcriptional regulator

 

SP1131

transcriptional regulator, putative

AR5

SP1134

hypothetical protein

 

SP1135

hypothetical protein

 

SP1136

hypothetical protein

 

SP1137

GTP-binding protein, putative

AR6

SP1315

V-type ATP synthase subunit D

 

SP1316

V-type ATP synthase subunit B

 

SP1317

V-type ATP synthase subunit A

 

SP1318

V-type ATP synthase subunit F

 

SP1319

V-type sodium ATP synthase, subunit C

 

SP1320

V-type sodium ATP synthase, subunit E

 

SP1321

V-type ATP synthase subunit K

 

SP1322

V-type ATP synthase subunit I

 

SP1323

hypothetical protein

 

SP1324

ROK family protein

 

SP1325

oxidoreductase, Gfo/Idh/MocA family

 

SP1326

neuraminidase, putative

 

SP1327

hypothetical protein

 

SP1328

sodium: solute symporter family protein

 

SP1329

N-acetylneuraminate lyase

 

SP1330

N-acetylmannosamine-6-phosphate 2-epimerase

 

SP1331

phosphosugar-binding transcriptional regulator, putative

AR7

SP1341

ABC transporter, ATP-binding protein

 

SP1342

toxin secretion ABC transporter, ATP-binding/permease protein

 

SP1343*

prolyl oligopeptidase family protein

 

SP1344*

hypothetical protein

AR8

SP1433

transcriptional regulator, AraC family

 

SP1434*

ABC transporter, ATP-binding/permease protein

 

SP1435

ABC transporter, ATP-binding protein

 

SP1436

hypothetical protein

AR8

SP1437

hypothetical protein

 

SP1438

ABC transporter, ATP-binding protein

AR9

SP1616

allulose-6-phosphate 3-epimerase

 

SP1617

PTS system, IIC component

 

SP1618

PTS system, IIB component

 

SP1619

PTS system, IIA component

 

SP1620

PTS system, nitrogen regulatory component IIA

 

SP1621

putative transcription anti terminator BglG family protein

 

SP1622

transposase, IS200 family

AR10

SP1738

guanylate kinase

 

SP1739

hypothetical protein

 

SP1740

hypothetical protein

AR11

SP1856*

transcriptional regulator, MerR family

 

SP1857

cation efflux system protein

 

SP1858

transcriptional regulator, TetR family

 

SP1859*

transporter, putative

 

SP1860

choline transporter

AR12

SP1896*

sugar ABC transporter, permease protein

 

SP1897

sugar ABC transporter, sugar-binding protein

 

SP1898*

alpha-galactosidase

AR13

SP2159

fucolectin-related protein

 

SP2160

hypothetical protein

 

SP2161

PTS system, IID component

 

SP2162

PTS system, IIC component

 

SP2163

PTS system, IIB component

  1. * contain virulence genes identified by signature tagged mutagenesis[41].