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Figure 1 | BMC Genomics

Figure 1

From: An integrative computational systems biology approach identifies differentially regulated dynamic transcriptome signatures which drive the initiation of human T helper cell differentiation

Figure 1

A schematic illustration of the LIGAP method. LIGAP implements a statistical analysis of multiple lineage commitment, as shown here, or other time-course profiles. LIGAP considers all possible comparisons between cell subsets, quantifies a probabilistic model fit for each partition, and summarizes the individual probabilities into differential regulation scores. The case of three lineages, Th0, Th1 and Th2 is shown.

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BMC Genomics

ISSN: 1471-2164

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