Table 1 Differentially expressed genes in T cells polarized towards the Th0, Th1 and Th2 subsets
Top 18 Th0 specific genes | Top 49 Th1 specific genes | Top 50 Th2 specific genes | ||||||
|---|---|---|---|---|---|---|---|---|
Affymetrix probe ID | Gene symbol | P(“Th0 specific”) | Affymetrix probe ID | Gene symbol | P(“Th1 specific”) | Affymetrix probe ID | Gene symbol | P(“Th2 specific”) |
203881_s_at | DMD(<2) | 0.99967984 | 206618_at | IL18R1(+) | 0.999997088 | 204388_s_at | MAOA(+) | 1 |
223435_s_at | PCDHA1(<2) | 0.999832654 | 203881_s_at | DMD(+) | 0.999993101 | 227006_at | PPP1R14A(+) | 1 |
205027_s_at | MAP3K8(<2) | 0.996290375 | 210354_at | IFNG(+) | 0.999987382 | 205419_at | GPR183(+) | 1 |
228055_at | NAPSB(<2) | 0.996196899 | 207072_at | IL18RAP(+) | 0.9999811558 | 215172_at | PTPN20A(+) | 1 |
220225_at | IRX4(<2) | 0.991324709 | 213943_at | TWIST1(+) | 0.999952924 | 205769_AT | SLC27A2(-) | 1 |
205794_s_at | NOVA1(<2) | 0.984972756 | 222547_at | MAP4K4(<2) | 0.999933552 | 218976_at | DNAJC12(-) | 1 |
221035_s_at | TEX14(<2) | 0.981445323 | 242809_at | IL1RL1(<2) | 0.999876515 | 208510_s_at | PPARG(+) | 1 |
210354_at | IFNG | 0.977204551 | 206007_at | PRG4(<2) | 0.999828413 | 228708_at | RAB27B(+) | 1 |
212012_s_at | KPNA6(<2) | 0.976438534 | 228055_at | NAPSB(+) | 0.99973265 | 45288_at | ABHD6(+) | 1 |
219265_at | MOBKL2B(<2) | 0.974857762 | 235458_at | HAVCR2(+) | 0.99959007 | 229764_at | TPGR1(+) | 1 |
212992_at | AHNAK2(<2) | 0.971558242 | 225955_at | METRIL(+) | 0.99954195 | 235199_at | RNF125(+) | 1 |
223727_at | KCNIP2(<2) | 0.968952518 | 206974_at | CXCR6(+) | 0.999495469 | 203153_at | IFIT1(-) | 1 |
200907_s_at | PALLD(<2) | 0.967031439 | 206785_s_at | KLRC2(<2) | 0.99882105 | 203097_s_at | RAPGEF2(-) | 1 |
1570169_at | CSMD2(<2) | 0.950549266 | 200648_s_at | GLUL(+) | 0.997745987 | 208891_at | DUSP6(+) | 1 |
200906_s_at | PALLD(<2) | 0.940149574 | 205027_s_at | MAP3K8(+) | 0.996774094 | 223159_s_at | NEK6(+) | 1 |
216341_s_at | GNRHR(<2) | 0.933169413 | 225142_at | JHDM1D(<2) | 0.996653927 | 210715_s_at | SPINT2(+) | 1 |
222890_at | CCDC113(<2) | 0.921542966 | 215672_s_at | AHCYL2(<2) | 0.996237492 | 208158_s_at | OSBPL1A(+) | 1 |
201283_s_at | TRAK1(<2) | 0.914512473 | 219383_at | PRR5L(<2) | 0.995895316 | 225752_at | NIPA1(+) | 1 |
220603_s_at | MCTP2(+) | 0.993459782 | 206638_at | HTR2B(+) | 1 | |||
239533_at | GPR155(<2) | 0.992909201 | 205579_at | HRH1(+) | 1 | |||
229603_at | BBS12(+) | 0.989517632 | 226508_s_at | TNFSF13B(-) | 0.999999999 | |||
237559_at | GPR55(<2) | 0.988653639 | 244413_at | CLECL1(+) | 0.999999999 | |||
204284_at | PPP1R3C(<2) | 0.988109742 | 203708_at | PDE4B(-) | 0.999999999 | |||
202625_at | LYN(<2) | 0.986582272 | 227438_at | ALPK1(-) | 0.999999998 | |||
223767_at | GPR84(<2) | 0.984948052 | 210762_s_at | DLC1(+) | 0.999999998 | |||
209348_s_at | MAF(+) | 0.983885642 | 235570_at | RBMS3(+) | 0.999999997 | |||
210448_s_at | P2RX5(+) | 0.9830704 | 212077_at | CALD1(+) | 0.999999997 | |||
228057_at | DDIT4L(<2) | 0.978509028 | 235301_at | KIAA1324L(+) | 0.999999997 | |||
203129_s_at | KIF5C(<2) | 0.978078282 | 209576_at | GNAI1(+) | 0.999999997 | |||
1554190_s_at | C10orf81(<2) | 0.976976156 | 1554878_a_at | ABCD3(+) | 0.999999996 | |||
228806_at | RORC(+) | 0.976176574 | 205569_at | LAMP3(+) | 0.999999996 | |||
227568_at | HECTD2(<2) | 0.975089149 | 205900_at | KRT1(+) | 0.999999996 | |||
219753_at | STAG3(+) | 0.972731568 | 210145_at | PLA2G4A(+) | 0.999999996 | |||
223374_s_at | B3GALNT1(<2) | 0.971777376 | 227529_s_at | AKAP12(+) | 0.999999995 | |||
205098_at | CCR1(<2) | 0.969847411 | 209602_s_at | GATA3(+) | 0.999999995 | |||
200907_s_at | PALLD(+) | 0.967031845 | 225566_at | NRP2(+) | 0.999999995 | |||
211122_s_at | CXCL11(<2) | 0.965307014 | 1552807_a_at | SIGLEC10(+) | 0.999999995 | |||
227697_at | SOCS3(+) | 0.965003456 | 220307_at | CD244(<2) | 0.999999994 | |||
212683_at | SLC23A44(<2) | 0.960505919 | 239151_at | BMS1P1(+) | 0.999999994 | |||
213572_s_at | SERPINB1(<2) | 0.953874496 | 221241_s_at | BCL214(-) | 0.999999993 | |||
244321_at | PGAP1(+) | 0.953326576 | 229625_at | GBP5(-) | 0.999999992 | |||
217127_at | CTH(+) | 0.947970476 | 204912_at | IL10RA(+) | 0.999999999 | |||
225962_at | ZNRF1(+) | 0.944840091 | 214974_x_at | CXCL5(-) | 0.999999989 | |||
219532_at | ELOVL4(<2) | 0.937454137 | 221971_x_at | CTGLF10P(+) | 0.999999989 | |||
222838_at | SLAMF7(+) | 0.934337899 | 203853_s_at | GAB2(+) | 0.999999989 | |||
228658 | MIAT(+) | 0.934243107 | 222457_s_at | LIMA1(+) | 0.999999986 | |||
206948_s_at | PMCH(<2) | 0.928324396 | 213385_at | CHN2(+) | 0.999999983 | |||
232030_at | KIAA1632(<2) | 0.914780073 | 205630_at | CRH(+) | 0.999999979 | |||
213596_at | CASP4(<2) | 0.907680384 | 207861_at | CCL22(+) | 0.999999979 | |||
219209_at | IFIH1(-) | 0.999999977 | ||||||