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Table 2 Principal component (PC) analysis of behavioural phenotypes in HAB x LAB derived F2 mice sorted by behavioural test paradigms

From: The endocrine stress response is linked to one specific locus on chromosome 3 in a mouse model based on extremes in trait anxiety

Phenotype

PC 1

PC 2

PC 3

PC 4

PC 5

PC 6

PC 7

HPA-RT – stress CORT [μg/l]

     

−0.97

 

HPA-RT – increase in CORT [μg/l]

     

−0.96

 

EPM – entries to the middle open arm

 

−0.96

     

EPM – entries to the distal open arm

 

−0.93

     

EPM – time on the distal open arm [s]

 

−0.92

     

EPM – time on the middle open arm [s]

 

−0.78

     

EPM – full open arm entries

 

−0.77

     

EPM – time spent on the proximal open arm [s]

    

−0.91

  

EPM – percentage of open arm entries

    

−0.89

  

EPM – percent time on the open arm

    

−0.84

  

EPM – total time on the open arm [s]

    

−0.81

  

EPM – all open arm entries

    

−0.77

  

FST – total swimming time [s]

   

0.91

   

FST – total floating time [s]

   

−0.9

   

OF – total distance travelled [m]

−0.89

      

OF – mean travelling speed [m/s]

−0.88

      

OF – total distance in the outer zone [m]

−0.84

      

OF – entries to the outer zone

−0.73

      

OF – total time in the outer zone [s]

  

0.97

    

OF – total time in the inner zone [s]

  

−0.96

    

OF – total distance in the inner zone [m]

  

−0.78

    

OF – latency to 1st entry of the outer zone [s]

  

−0.77

    

PHYS – daily water intake per g bodyweight [ml/g*d]

      

−0.95

PHYS – total daily water intake [ml/d]

      

−0.9