Table 3 Gene ontology (GO) terms enriched in LSRN and DE sets of genes expressed in LG/J and SM/J strain tibialis anterior muscle
From: Resolving candidate genes of mouse skeletal muscle QTL via RNA-Seq and expression network analyses
GO-Terms enriched | DE genes | LSRN genes | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Category | Go-Term | Go-Description | Count | % | PValue | Fold Enrichment | Benjamini | Count | % | PValue | Fold Enrichment | Benjamini |
GOTERM_CC_FAT | GO:0043292 | contractile fiber | 18 | 1.83 | 1.87E-06 | 4.01 | 9.10E-05 | 16 | 3.02 | 7.06E-08 | 5.88 | 6.99E-06 |
GOTERM_CC_FAT | GO:0044449 | contractile fiber part | 17 | 1.73 | 2.20E-06 | 4.18 | 9.36E-05 | 15 | 2.84 | 1.31E-07 | 6.09 | 9.70E-06 |
GOTERM_CC_FAT | GO:0030016 | myofibril | 18 | 1.83 | 9.98E-07 | 4.18 | 5.67E-05 | 16 | 3.02 | 3.89E-08 | 6.14 | 1.16E-05 |
GOTERM_CC_FAT | GO:0044429 | mitochondrial part | 49 | 4.99 | 7.64E-06 | 1.98 | 2.61E-04 | 36 | 6.81 | 2.55E-06 | 2.40 | 1.51E-04 |
GOTERM_CC_FAT | GO:0016460 | myosin II complex | 6 | 0.61 | 1.38E-04 | 10.58 | 3.36E-03 | 6 | 1.13 | 1.24E-05 | 17.46 | 6.13E-04 |
GOTERM_CC_FAT | GO:0005759 | mitochondrial matrix | 21 | 2.14 | 8.33E-05 | 2.73 | 2.36E-03 | 17 | 3.21 | 1.70E-05 | 3.64 | 7.23E-04 |
GOTERM_CC_FAT | GO:0031980 | mitochondrial lumen | 21 | 2.14 | 8.33E-05 | 2.73 | 2.36E-03 | 17 | 3.21 | 1.70E-05 | 3.64 | 7.23E-04 |
GOTERM_CC_FAT | GO:0032982 | myosin filament | 6 | 0.61 | 4.65E-04 | 8.46 | 9.87E-03 | 6 | 1.13 | 4.37E-05 | 13.97 | 1.62E-03 |
GOTERM_CC_FAT | GO:0016459 | myosin complex | 11 | 1.12 | 5.18E-04 | 3.82 | 1.03E-02 | 10 | 1.89 | 5.33E-05 | 5.73 | 1.76E-03 |
GOTERM_CC_FAT | GO:0005859 | muscle myosin complex | 5 | 0.51 | 8.20E-04 | 10.58 | 1.26E-02 | 5 | 0.95 | 1.20E-04 | 17.46 | 2.73E-03 |
GOTERM_CC_FAT | GO:0005739 | mitochondrion | 94 | 9.58 | 4.62E-05 | 1.50 | 1.43E-03 | 62 | 11.72 | 1.02E-04 | 1.64 | 2.75E-03 |
GOTERM_CC_FAT | GO:0005740 | mitochondrial envelope | 34 | 3.47 | 8.90E-04 | 1.84 | 1.31E-02 | 24 | 4.54 | 8.65E-04 | 2.14 | 1.50E-02 |
GOTERM_MF_FAT | GO:0017076 | purine nucleotide binding | 117 | 11.93 | 1.90E-04 | 1.38 | 4.57E-02 | 80 | 15.12 | 6.56E-05 | 1.54 | 1.85E-02 |
GOTERM_CC_FAT | GO:0005863 | striated muscle thick filament | 4 | 0.41 | 4.90E-03 | 10.58 | 6.24E-02 | 4 | 0.76 | 1.16E-03 | 17.46 | 1.90E-02 |
GOTERM_CC_FAT | GO:0044421 | extracellular region part | 65 | 6.63 | 6.92E-06 | 1.78 | 2.62E-04 | 38 | 7.18 | 1.42E-03 | 1.71 | 2.20E-02 |
GOTERM_CC_FAT | GO:0005743 | mitochondrial inner membrane | 28 | 2.85 | 8.09E-04 | 2.00 | 1.31E-02 | 19 | 3.59 | 2.12E-03 | 2.24 | 2.96E-02 |
GOTERM_CC_FAT | GO:0031966 | mitochondrial membrane | 31 | 3.16 | 2.53E-03 | 1.78 | 3.39E-02 | 22 | 4.16 | 2.04E-03 | 2.09 | 2.98E-02 |