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Table 2 Summary of differentially expressed genes involved in insecticide resistance of Cimex lectularius

From: RNA-Seq and molecular docking reveal multi-level pesticide resistance in the bed bug

Mode of resistance Number Number in the top 5,000 differentials qRT-PCR validated
   Up-regulated Down-regulated  
Metabolic resistance     
Cytochrome P450 102 19 10 BB_Contig_103, 18015, 19601, 22399
ABC transporters 27 8 2 BB_Contig_1346
GSTs 18 3 1 NA
Catalase 13 2 0 NA
Superoxide dismutase 6 1 1 BB_Contig_49102
Carboxylesterases 6 2 0 NA
Glutathione peroxidase 7 3 0 NA
Penetration resistance     
Cuticular proteins 247 46 8 BB_Contig_1762,1766, 17694, 21630, 48951
Insecticidal targets     
Acetylcholinesterases 6 3 0 BB_Contig_3653