Figure 4

Confirmation of a candidate XCI escapee gene. The figure displays results from RNA-FISH experiments on female embryonic fibroblasts. The upper panel shows a cell with biallelic RNA signals for the candidate gene Tmem29, which escaped in 12% of the cells (82 cells counted). The lower panel shows a cell with biallelic RNA signals for a positive control for escape, Kdm5c, which escaped in 25% of the cells (52 cells counted).