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Table 1 Classification of detoxification gene families in Drosophila melanogaster , Anopheles gambiae , Aedes aegypti , and Culex pipiens quinquefasciatus

From: Transcriptomic and phylogenetic analysis of Culex pipiens quinquefasciatus for three detoxification gene families

  D. melanogaster A. gambiae A. aegypti C. p. quinquefasciatus
CCE     
Dietary/detoxification*     
B class (α-esterases) 13 16 22 30 (18)
Hormone/semiochemical processing     
D class (integument esterases) 3 0 0 1 (0)
E class (β-esterases) 2 4 2 3 (3)
F class (dipteran JH esterases) 3 6 7 13 (5)
G class (lepidopteran JH esterases) 0 4 6 9 (6)
Neuro/developmental     
H class (glutactins) 5 10 7 6 (5)
I class (unknown) 1 1 1 1 (1)
J class (acetylcholinesterases) 1 2 2 2 (2)
K class (gliotactins) 1 1 1 1 (1)
L class (neuroligins) 4 5 5 3 (3)
M class (neurotactins) 2 2 2 2 (2)
Total 35 51 55 71 (46)
P450     
CYP2 6 10 11 14 (12)
CYP3 (include CYP6 and CYP9) 36 42 84 88 (72)
CYP4 32 45 59 83 (58)
Mitochondrial 11 9 10 11 (8)
Total 85 106 164 196 (150)
GST     
Delta 11 12 8 14 (13)
Epsilon 14 8 8 10 (6)
Omega 5 1 1 1 (1)
Sigma 1 1 1 1 (1)
Theta 4 2 4 6 (6)
Zeta 2 1 1 0 (0)
Others 0 3 3 3 (2)
Total 37 28 26 35 (29)
  1. *The dietary/detoxification functional group follows the new system proposed by Oakeshott et al. (2010).
  2. Data of D. melanogaster, An. gambiae, and Ae. aegypti are taken from Oakeshott et al. (2010).
  3. The number of C. p. quinquefasciatus genes in brackets is from the DGE libraries.
  4. CCE, carboxyl/cholinesterases; P450, cytochrome P450 monooxygenases; GST, glutathione S-transferases.