TY - JOUR AU - Kuhn, Alexandre AU - Kumar, Azad AU - Beilina, Alexandra AU - Dillman, Allissa AU - Cookson, Mark R. AU - Singleton, Andrew B. PY - 2012 DA - 2012/11/12 TI - Cell population-specific expression analysis of human cerebellum JO - BMC Genomics SP - 610 VL - 13 IS - 1 AB - Interpreting gene expression profiles obtained from heterogeneous samples can be difficult because bulk gene expression measures are not resolved to individual cell populations. We have recently devised Population-Specific Expression Analysis (PSEA), a statistical method that identifies individual cell types expressing genes of interest and achieves quantitative estimates of cell type-specific expression levels. This procedure makes use of marker gene expression and circumvents the need for additional experimental information like tissue composition. SN - 1471-2164 UR - https://doi.org/10.1186/1471-2164-13-610 DO - 10.1186/1471-2164-13-610 ID - Kuhn2012 ER -