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Table 2 Orthologous gene clusters with evidence for positive selection

From: Comparative genomics of bacteria in the genus Providencia isolated from wild Drosophila melanogaster

Annotation

SEED Subsystem1

EC2

p-value

homocysteine methyltransferase

methionine biosynthesis

2.1.1.14

0.000496

xanthine/uracil/thiamine/ascorbate permease family protein

purine utilization

-

0.002595

TolC precursor

multidrug efflux pumps

-

0.003340

acetate permease ActP

acetogenesis from pyruvate

-

0.003703

hypothetical protein with DUF177

-

-

0.007188

2-octaprenyl-6-methoxyphenol hydroxylase

ubiquinone biosynthesis

1.14.13.-

0.009478

UDP-N-acetylglucosamine

-

2.4.2.227

0.010464

D-tyrosyl-tRNA(Tyr) deacylase

stringent response

-

0.014392

sulfate transport system permease protein CysT

cysteine biosynthesis

-

0.014526

yihD

-

-

0.015702

antibiotic biosynthesis monooxygenonase

-

-

0.015830

4-diphosphocytidyl-2-C-methyl-derythritol kinase

isoprenoid biosynthesis

2.7.1.148

0.018713

Acyl-phosphate:glycerol-3-phosphate O-acyltransferase PlsY

glycerolipid and glycerophospholipid metabolism

-

0.021835

dethiobiotin synthetase

biotin biosynthesis

6.3.3.3

0.029052

LSU ribosomal protein L9p

ribosomal LSU

-

0.029278

Ribonuclease E

ribosomal biogenesis, RNA processing & degradation protein glycerolipid and glycerophospholipid metabolism

3.1.26.12

0.030756

acyl carrier

-

0.031606

predicted Fe-S oxidoreductase

-

-

0.041952

flagellar transcription activator FlhC

flagellum

-

0.044270

magnesium transporter

-

-

0.048181

  1. P-values were calculated using codeml within PAML[41] by comparing models M8a and M8 and are uncorrected for multiple testing.
  2. 1The subsystem and protein function designation were determined through annotation with RAST[23] with the exception of the proteins annotated as antibiotic biosynthesis monooxygenonase which was designated by Blast2GO[24].
  3. 2Enzyme Commission number.