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Table 1 Results from relative-rate tests based on nucleotide single-gene alignments and mt and nuclear nucleotide data sets

From: The origin of modern frogs (Neobatrachia) was accompanied by acceleration in mitochondrial and nuclear substitution rates

 

Mean weighted substitution rates

Probability of relative-rate tests

gene

K1

K2

K3

K4

p (1 vs. 2) p < 0.05

p (1 vs. 3) p < 0.0167

p (1 vs. 4) p < 0.0167

p (3 vs. 4) p < 0.0167

atp6

0.427863

0.473377

0.481832

0.455958

0.014730*

0.005722*

0.105996

0.139169

atp8

0.548420

0.597954

0.603741

0.598698

0.262944

0.238598

0.273487

0.916317

cob

0.357846

0.395422

0.400600

0.376129

0.153630

0.127295

0.461317

0.438624

cox1

0.258230

0.291037

0.294927

0.288984

1.26·10 -4 *

4.86·10 -5 *

4.59·10 -5 *

0.475097

cox2

0.279140

0.349751

0.355794

0.328478

6.31·10 -6 *

3.76·10 -6 *

5.41·10 -4 *

0.068572

cox3

0.289143

0.322240

0.328289

0.304404

0.007560*

0.002549*

0.170152

0.046288

nad1

0.371027

0.401329

0.413424

0.383640

0.023124*

0.002486*

0.296321

0.020798

nad2

0.507982

0.547513

0.548407

0.525736

0.025438*

0.026856

0.251499

0.170942

nad3

0.434548

0.430927

0.434119

0.433411

0.869559

0.985402

0.956541

0.974496

nad4

0.431683

0.557581

0.560891

0.590991

1.00·10 -7 *

1.00·10 -7 *

1.00·10 -7 *

0.050825

nad4L

0.497599

0.631415

0.643682

0.588595

8.27·10 -4 *

6.30·10 -4 *

0.009870*

0.150316

nad5

0.411432

0.519950

0.517924

0.538763

1.00·10 -7 *

1.00·10 -7 *

1.00·10 -7 *

0.081618

nad6

0.463362

0.505592

0.512071

0.518343

0.088626

0.056897

0.026638

0.765287

rrnS

0.191816

0.26154

0.265755

0.253359

1.00·10 -7 *

1.00·10 -7 *

9,73 ·10 -3 *

0.267807

rrnL

0.193460

0.217439

0.219738

0.214547

0.005620*

0.003273*

0.0176213

0.516844

tRNAs

0.272203

0.309978

0.312829

0.299828

0.001434*

0.000809*

0.010368*

0.221773

all mt genes

0.330116

0.379173

0.384017

0.372441

1.00·10 -7 *

1.00·10 -7 *

1.00·10 -7 *

0.001898*

bdnf

0.162298

0.183220

0.183143

0.188813

0.063971

0.066639

0.019606

0.425053

cxcr4

0.305898

0.310540

0.310616

0.317277

0.749761

0.760622

0.463425

0.635922

h3a

0.072185

0.071813

0.074309

0.069597

0.967280

0.831715

0.787527

0.662899

pomc

0.383197

0.374114

0.370759

0.381447

0.747452

0.671607

0.956266

0.667038

rag1

0.278115

0.298226

0.297262

0.300048

0.177027

0.210499

0.172426

0.837948

rag2

0.436022

0.493728

0.494946

0.512607

0.002539*

0.003285*

2.38·10 -4 *

0.314455

rho

0.177431

0.164405

0.167539

0.177528

0.444978

0.596616

0.995982

0.609647

slc8a1

0.236296

0.253733

0.253592

0.255299

0.029208*

0.041528

0.030535

0.840326

slc8a3

0.223439

0.233366

0.232416

0.238298

0.280968

0.356872

0.115003

0.460431

all nuc genes

0.067158

0.075283

0.074880

0.072843

0.036588*

0.055309

0.164760

0.607197

  1. K values are mean weighted substitution rates for (1) non-neobatrachians, (2) all neobatrachians, (3), species-poor neobatrachians (Heleophrynidae, Calyptocephalellidae, Limnodynastidae, Sooglossoidea), and (4) species-rich neobatrachians (Ranoides and Nobleobatrachia). Probabilities (p) of relative-rate tests correspond to the comparisons between the different groups (shown in parentheses). Statistically significant results (p < 0.05; or p < 0.05/3 = 0.0167 to correct for multiple testing) are in bold italics and marked with an asterisk. Abbreviations of mt genes follow [44]; see main text for full names of nuclear genes.