No. | Gene symbol (RGD) | Protein name; description |
---|---|---|
Voltage-gated cation channels | ||
1 | Cacna1g | Ca2+ channel, voltage-gated, α1G subunit |
2 | Cacna2d1 | Ca2+ channel, voltage-gated, α2/δ1 subunit |
3 | Cacna2d2 | Ca2+ channel, voltage-gated, α2/δ2 subunit |
4 | Kcna1 | K+ voltage-gated, shaker-related subfamily member 1 |
5 | Kcna6 | K+ voltage-gated, shaker-related subfamily member 6 |
6 | Kcnh4 | K+ voltage-gated, subfamily H member 4 |
7 | Kcnh8 | K+ voltage-gated, subfamily H member 8 |
8 | Kcnj3 | K+ inwardly rectifying channel, subfamily J member 3 |
9 | Scn8a | Na+ voltage-gated, type VIII, alpha subunit |
Neurotransmitter receptors | ||
10 | Cnr1 | Cannabinoid CB1 receptor; metabotropic |
11 | Drd3 | Dopamine D3 receptor; metabotropic |
12 | Gabra3 | GABAAα3 receptor; ionotropic (Cl-) |
13 | Gabrg2 | GABAAγ2 receptor; ionotropic (Cl-) |
14 | Glra1 | Glycine α1 receptor; ionotropic |
15 | Gria3 | Glutamate AMPA 3 receptor; ionotropic |
16 | Grid2 | Glutamate δ2 receptor; ionotropic |
17 | Grik3 | Glutamate kainate 3 receptor; ionotropic |
18 | Htr1b | 5-hydroxytryptamine (serotonin) 1B receptor; metabotropic |
19 | Htr3a | Serotonin 3A receptor; ionotropic |
20 | Htr3b | Serotonin 3B receptor; ionotropic |
Synaptic vesicle proteins | ||
21 | Syt1 | Synaptotagmin I; membrane protein, Ca2+ sensor involved in vesicle trafficking and neurotransmitter release |
22 | Syt4 | Synaptotagmin IV; membrane protein, vesicle trafficking and neurotransmitter release |
23 | Syt5 | Synaptotagmin V; membrane protein, Ca2+ sensor involved in vesicle trafficking and neurotransmitter release |
24 | Syt6 | Synaptotagmin VI; membrane protein, Ca2+ sensor involved in vesicle trafficking and neurotransmitter release |
25 | Syt7 | Synaptotagmin VII; membrane protein, Ca2+ sensor involved in vesicle trafficking and neurotransmitter release |
26 | Syp | Synaptophysin; synaptic vesicle organization |
27 | Vamp2 | Vesicle-associated membrane protein 2; vesicle transport and membrane fusion during exocytosis |
28 | Vamp3 | Vesicle-associated membrane protein 3; vesicle transport and membrane fusion during exocytosis |
Structural synaptic proteins | ||
29 | Cdh2 | Cadherin 2 (alias N-cadherin); hemophilic cell adhesion molecule in excitatory synapses |
30 | Cnksr2 | Connector enhancer of kinase suppressor of Ras 2; scaffold protein, complex assembly of synaptic proteins |
31 | Dfnb31 | Deafness autosomal recessive 31; PDZ scaffold protein, facilitates synaptic transmission |
32 | Gabarap | GABAA receptor-associated protein; involved in clustering of neurotransmitter receptors |
33 | Lin7a | Homolog a of C. elegans lin-7; PDZ scaffold protein, localizes vesicles and receptors to the plasma membrane |
34 | Map1b | Microtubule-associated protein; involved in synaptic plasticity |
35 | Mpdz | Multiple PDZ domain protein; PDZ scaffold protein, component of NMDA receptor signaling complex |
36 | Nlgn1 | Neuroligin 1; synaptic cell adhesion molecule, maintains synaptic junctions by binding β-neurexins |
37 | Nlgn2 | Neuroligin 2; synaptic cell-adhesion molecule, maintains synaptic junctions by binding β-neurexins |
38 | Nrxn3 | Neurexins 3; synaptic cell-adhesion molecule; maintains synaptic junctions by binding neuroligins |
Other proteins involved in modulation of signal transmission | ||
39 | Gjd2 | Gap junction protein delta; member of the connexin family, in gap-junction channels of electrical synapses |
40 | App | Amyloid β (A4) precursor protein; cell surface receptor involved in synaptic plasticity |
41 | Calb2 | Calbindin 2 (alias calretinin); Ca2+-binding protein, modulates neuronal excitability |