Figure 4

Hamming distances among enzymes in Uniprot data. Statistics of Hamming distances between 6.1.1.9 (A-C) sequences and 6.1.1.18 sequences (D-F) in Uniprot KB Data. Top: Differences between strains of the same species (A, D). Middle: Differences between species of the same genus (B, E). Bottom: differences between genera in the same family (C, F). Insets in (A, B) display results for low distances and demonstrate the lack of clear cut-off between species and strains for 6.1.1.9 in contrast with the clear cut-off at distance 2 for 6.1.1.18 enzymes.