TY - JOUR AU - Ehret, G. PY - 2011 DA - 2011// TI - Genome-wide association studies: contribution of genomics to understanding blood pressure and essential hypertension JO - Curr Hypertens Rep VL - 12 UR - https://doi.org/10.1007/s11906-009-0086-6 DO - 10.1007/s11906-009-0086-6 ID - Ehret2011 ER - TY - JOUR AU - Lupski, J. R. AU - Belmont, J. W. AU - Boerwinkle, E. AU - Gibbs, R. A. PY - 2011 DA - 2011// TI - Clan genomics and the complex architecture of human disease JO - Cell VL - 147 UR - https://doi.org/10.1016/j.cell.2011.09.008 DO - 10.1016/j.cell.2011.09.008 ID - Lupski2011 ER - TY - JOUR AU - Liu, D. J. AU - Leal, S. M. PY - 2010 DA - 2010// TI - A novel adaptive method for the analysis of next-generation sequencing data to detect complex trait associating with rare variants due to gene main effects and interactions JO - PLoS Genet VL - 6 UR - https://doi.org/10.1371/journal.pgen.1001156 DO - 10.1371/journal.pgen.1001156 ID - Liu2010 ER - TY - JOUR AU - Xiong, M. AU - Zhao, J. AU - Boerwinkle, E. PY - 2002 DA - 2002// TI - Generalized T2 test for genome association studies JO - Am J Hum Genet VL - 70 UR - https://doi.org/10.1086/340392 DO - 10.1086/340392 ID - Xiong2002 ER - TY - JOUR AU - Madsen, B. E. AU - Browning, S. R. PY - 2009 DA - 2009// TI - A groupwise association test for rare mutations using a weighted sum statistics JO - PLoS Genet VL - 5 UR - https://doi.org/10.1371/journal.pgen.1000384 DO - 10.1371/journal.pgen.1000384 ID - Madsen2009 ER - TY - JOUR AU - Mukhopadhyay, I. AU - Feingold, E. AU - Weeks, D. E. AU - Thalamuthu, A. PY - 2010 DA - 2010// TI - Association tests using kernel-based measures of multi-locus genotype similarity between individuals JO - Genet Epidemiol VL - 34 ID - Mukhopadhyay2010 ER - TY - JOUR AU - Price, A. L. AU - Kryukov, G. V. AU - Bakker, P. I. W. AU - Purcell, S. M. AU - Staples, J. AU - Wei, L. J. AU - Sunyaev, S. R. PY - 2010 DA - 2010// TI - Pooled association tests for rare variants in exon-resequencing studies JO - Am J Hum Genet VL - 86 UR - https://doi.org/10.1016/j.ajhg.2010.05.014 DO - 10.1016/j.ajhg.2010.05.014 ID - Price2010 ER - TY - JOUR AU - Wu, M. C. AU - Lee, S. AU - Cai, T. AU - Li, Y. AU - Boehnke, M. AU - Lin, X. PY - 2011 DA - 2011// TI - Rare variant association testing for sequencing data using the sequence kernel association test (SKAT) JO - Am J Hum Genet VL - 89 UR - https://doi.org/10.1016/j.ajhg.2011.05.029 DO - 10.1016/j.ajhg.2011.05.029 ID - Wu2011 ER - TY - JOUR AU - Luo, L. AU - Boerwinkle, E. AU - Xiong, M. PY - 2011 DA - 2011// TI - Association studies for next-generation sequencing JO - Genome Res VL - 21 UR - https://doi.org/10.1101/gr.115998.110 DO - 10.1101/gr.115998.110 ID - Luo2011 ER - TY - JOUR AU - Neale, B. M. AU - Rivas, M. A. AU - Voight, B. F. AU - Altshuler, D. AU - Devlin, B. AU - Orho-Melander, M. AU - Kathiresan, S. AU - Purcell, S. M. AU - Roeder, K. AU - Daly, M. J. PY - 2011 DA - 2011// TI - Testing for an unusualdistribution of rare variants JO - PLoS Genet VL - 7 UR - https://doi.org/10.1371/journal.pgen.1001322 DO - 10.1371/journal.pgen.1001322 ID - Neale2011 ER - TY - JOUR AU - Han, F. AU - Pan, W. PY - 2010 DA - 2010// TI - A data-adaptive sum test for disease association with multiple common or rare variants JO - Hum Hered VL - 70 UR - https://doi.org/10.1159/000288704 DO - 10.1159/000288704 ID - Han2010 ER - TY - JOUR AU - Lin, D. Y. AU - Tang, Z. Z. PY - 2011 DA - 2011// TI - A general framework for detecting disease associations with rare variants in sequencing studies JO - Am J Hum Genet VL - 89 UR - https://doi.org/10.1016/j.ajhg.2011.07.015 DO - 10.1016/j.ajhg.2011.07.015 ID - Lin2011 ER - TY - JOUR AU - Bansal, V. AU - Libiger, O. AU - Torkamani, A. AU - Schork, N. J. PY - 2010 DA - 2010// TI - Statistical analysis strategies for association studies involving rare variants JO - Nat Rev Genet VL - 11 UR - https://doi.org/10.1038/nrg2867 DO - 10.1038/nrg2867 ID - Bansal2010 ER - TY - JOUR AU - Basu, S. AU - Pan, W. PY - 2010 DA - 2010// TI - Comparison of statistical tests for disease association with rare variants JO - Genet Epidemiol VL - 10 ID - Basu2010 ER - TY - JOUR AU - Feng, T. AU - Elston, R. C. AU - Zhu, X. PY - 2011 DA - 2011// TI - Detecting rare and common variants for complex traits: sibpair and odds ratio weighted sum statistics (SPWSS, ORWSS) JO - Genet Epidemiol VL - 35 UR - https://doi.org/10.1002/gepi.20588 DO - 10.1002/gepi.20588 ID - Feng2011 ER - TY - JOUR AU - Thornton, T. AU - McPeek, M. S. PY - 2010 DA - 2010// TI - Roadtrips: Case–control association testing with partially or completely unknown population and pedigree structure JO - Am J Hum Genet VL - 86 UR - https://doi.org/10.1016/j.ajhg.2010.01.001 DO - 10.1016/j.ajhg.2010.01.001 ID - Thornton2010 ER - TY - JOUR AU - Yang, J. AU - Benyamin, B. AU - McEvoy, B. P. AU - Gordon, S. AU - Henders, A. K. AU - Nyholt, D. R. PY - 2010 DA - 2010// TI - Common SNPs explain a large proportion of the heritability for human height JO - Nat Genet VL - 42 UR - https://doi.org/10.1038/ng.608 DO - 10.1038/ng.608 ID - Yang2010 ER - TY - JOUR AU - Lambert, B. W. AU - Terwilliger, J. D. AU - Weiss, K. M. PY - 2008 DA - 2008// TI - ForSim: a tool for exploring the genetic architecture of complex traits with controlled truth JO - Bioinformatics VL - 24 UR - https://doi.org/10.1093/bioinformatics/btn317 DO - 10.1093/bioinformatics/btn317 ID - Lambert2008 ER - TY - JOUR AU - Li, Y. AU - Byrnes, A. E. AU - Li, M. PY - 2010 DA - 2010// TI - To identify associations with rare variants, Just WhaIT: weighted haplotype and imputation-based tests JO - Am J Hum Genet VL - 87 UR - https://doi.org/10.1016/j.ajhg.2010.10.014 DO - 10.1016/j.ajhg.2010.10.014 ID - Li2010 ER - TY - JOUR AU - Larson, M. G. AU - Atwood, L. D. AU - Benjamin, E. J. AU - Gupples, L. A. PY - 2007 DA - 2007// TI - Framingham Heart Study 100 K project: genome-wide associations for cardiovascular disease outcomes JO - BMC Med Genet VL - 8 UR - https://doi.org/10.1186/1471-2350-8-S1-S5 DO - 10.1186/1471-2350-8-S1-S5 ID - Larson2007 ER - TY - JOUR AU - Kannel, W. B. AU - Feinleib, M. AU - McNamara, P. M. AU - Garrison, R. J. AU - Castelli, W. P. PY - 1979 DA - 1979// TI - An investigation of coronary heart disease in families. The Framingham offspring study JO - Am J Epidemiol VL - 110 ID - Kannel1979 ER - TY - CHAP AU - Aye, T. T. AU - Soni, S. AU - van Veen, T. A. AU - van der Heyden, M. A. AU - Cappadona, S. AU - Varro, A. AU - de Weger, R. A. AU - de Jonge, N. AU - Vos, M. A. AU - Heck, A. J. AU - Scholten, A. PY - 2011 DA - 2011// TI - Reorganized PKA-AKAP associations in the failing human heart BT - J Mol Cell Cardiol ID - Aye2011 ER - TY - JOUR AU - Kuhn, C. AU - Frank, D. AU - Will, R. AU - Jaschinski, C. AU - Frauen, R. AU - Katus, H. A. AU - Frey, N. PY - 2009 DA - 2009// TI - DYRK1A is a novel negative regulator of cardiomyocyte hypertroply JO - J Biol Chem VL - 284 UR - https://doi.org/10.1074/jbc.M109.006759 DO - 10.1074/jbc.M109.006759 ID - Kuhn2009 ER - TY - JOUR AU - Parsa, A. AU - Chang, Y. P. C. AU - Kelly, R. J. AU - Corretti, M. C. AU - Ryan, K. A. AU - Robinson, S. W. AU - Gottlieb, S. S. AU - Kardia, S. L. R. AU - Shuldiner, A. R. AU - Liggett, S. B. PY - 2011 DA - 2011// TI - Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality JO - Clin Transl Sci VL - 4 UR - https://doi.org/10.1111/j.1752-8062.2010.00251.x DO - 10.1111/j.1752-8062.2010.00251.x ID - Parsa2011 ER - TY - JOUR AU - Thornton, T. AU - McPeek, M. S. PY - 2007 DA - 2007// TI - Case–control association testing with related individuals: a more powerful quasi-likelihood score test JO - Am J Hum Genet VL - 81 UR - https://doi.org/10.1086/519497 DO - 10.1086/519497 ID - Thornton2007 ER -