Table 4 P-values of four statistics for testing the association of a gene with CVD in Framingham Heart Study
From: Weighted pedigree-based statistics for testing the association of rare variants
Gene | Number of SNPs | χ2 | Collapsing | VT | WSS |
|---|---|---|---|---|---|
B4GALNT2 | 6 | 2.01E-03 | 2.10E-04 | 2.27E-03 | 6.00E-05 |
AKAP7 | 3 | 6.38E-02 | 6.61E-04 | 1.42E-02 | 1.00E-04 |
BOMB | 5 | 2.48E-03 | 3.51E-03 | 8.16E-04 | 3.00E-04 |
STX11 | 4 | 1.35E-02 | 3.11E-03 | 7.78E-04 | 3.60E-04 |
PIWIL3 | 4 | 5.89E-02 | 8.67E-03 | 1.06E-02 | 4.50E-04 |
CRY1 | 10 | 5.87E-04 | 4.92E-01 | 2.84E-02 | 4.70E-04 |
PTGES3 | 7 | 3.57E-02 | 1.40E-02 | 6.42E-03 | 5.46E-04 |
HMSD | 8 | 9.62E-03 | 7.65E-01 | 3.33E-02 | 8.38E-04 |
MNB/DYRK | 9 | 1.02E-02 | 4.87E-02 | 3.64E-02 | 8.85E-04 |
PIK3R4 | 5 | 2.89E-03 | 5.51E-01 | 5.79E-04 | 1.01E-03 |
MAP3K5 | 19 | 7.57E-02 | 9.61E-02 | 2.36E-03 | 1.31E-03 |
ZNF823 | 3 | 2.78E-02 | 1.18E-03 | 1.58E-02 | 1.34E-03 |
CTCF | 3 | 1.12E-01 | 3.83E-02 | 1.73E-01 | 1.36E-03 |
TRPC4 | 14 | 4.15E-02 | 5.99E-02 | 7.32E-04 | 1.50E-03 |
OSBPL9 | 12 | 9.09E-03 | 1.45E-04 | 1.83E-02 | 1.53E-03 |
DYRK1A | 12 | 1.47E-02 | 7.78E-02 | 3.47E-02 | 1.58E-03 |
FAM19A2 | 13 | 2.65E-01 | 2.28E-03 | 9.43E-03 | 1.60E-03 |
MRPS18C | 12 | 2.19E-03 | 5.37E-03 | 2.51E-03 | 1.63E-03 |
FAM175A | 9 | 2.43E-03 | 3.51E-03 | 2.11E-03 | 1.67E-03 |
ZNF714 | 6 | 3.40E-03 | 1.16E-02 | 2.39E-03 | 1.85E-03 |
AGPAT5 | 9 | 1.96E-02 | 1.68E-01 | 6.85E-03 | 1.94E-03 |