Skip to main content
Figure 11 | BMC Genomics

Figure 11

From: The genome of Pelobacter carbinolicus reveals surprising metabolic capabilities and physiological features

Figure 11

One - carbon unit production in P . carbinolicus . One-carbon units carried by tetrahydrofolate (THF) derive from serine, producing glycine. In the absence of the glycine cleavage complex, excess glycine might be deaminated to glyoxalate by aminotransferases using pyridoxal-5-phosphate (PLPO). Fusion of two glyoxalate molecules by glyoxalate carboligase, rearrangement to hydroxypyruvate with the aid of glutathione (GT), and amination would regenerate serine. An alternative pathway involving phosphorylation allows hydroxypyruvate to enter glycolysis to be catabolized.

Back to article page