Table 1 Gene set enrichment analysis (GSEA)
Group | Gene set | Size | ES | NES | p value | FDR |
|---|---|---|---|---|---|---|
Enriched in CDH | ||||||
1 | nucleosome | 14 | 0.76 | 2.34 | 0.00 | 0.84 |
2 | structural constituent of eye lens | 12 | 0.72 | 2.16 | 0.00 | 6.16 |
3 | inner ear morphogenesis | 21 | 0.61 | 2.15 | 0.00 | 4.38 |
4 | nucleosome assembly | 21 | 0.59 | 2.03 | 0.00 | 11.71 |
5 | chromatin assembly | 21 | 0.59 | 2.03 | 0.00 | 9.36 |
6 | intramolecular oxidoreductase activity | 16 | 0.61 | 1.96 | 0.01 | 14.74 |
7 | DNA-dependent DNA replication | 19 | 0.53 | 1.85 | 0.00 | 31.63 |
8 | DNA packaging | 24 | 0.50 | 1.82 | 0.00 | 33.31 |
9 | methylation | 43 | 0.41 | 1.78 | 0.00 | 40.09 |
10 | methyltransferase activity | 43 | 0.41 | 1.78 | 0.00 | 36.08 |
Enriched in MDH | ||||||
1 | proteasomal ubiquitin-dependent protein catabolic process | 60 | −0.51 | −2.01 | 0.00 | 12.63 |
2 | proteasomal protein catabolic process | 60 | −0.51 | −2.01 | 0.00 | 6.32 |
3 | ubiquitin-protein ligase activity | 71 | −0.49 | −1.93 | 0.00 | 14.41 |
4 | protein ubiquitination | 94 | −0.46 | −1.92 | 0.00 | 13.14 |
5 | regulation of protein catabolic process | 10 | −0.75 | −1.92 | 0.00 | 10.60 |
6 | protein modification by small protein conjugation | 101 | −0.45 | −1.90 | 0.00 | 11.47 |
7 | ubiquitin thiolesterase activity | 33 | −0.54 | −1.88 | 0.00 | 13.19 |
8 | thiolester hydrolase activity | 42 | −0.51 | −1.87 | 0.00 | 12.49 |
9 | protein modification by small protein conjugation or removal | 123 | −0.43 | −1.87 | 0.00 | 11.58 |
10 | membrane raft | 65 | −0.47 | −1.86 | 0.00 | 11.47 |
11 | cellular protein catabolic process | 129 | −0.42 | −1.86 | 0.00 | 10.68 |
12 | proteolysis involved in cellular protein catabolic process | 129 | −0.42 | −1.86 | 0.00 | 9.79 |