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Figure 2 | BMC Genomics

Figure 2

From: Pan-histone deacetylase inhibitors regulate signaling pathways involved in proliferative and pro-inflammatory mechanisms in H9c2 cells

Figure 2

PCA and clustered heat maps of DEGs in the H9c2 cells treated with TSA for 6 and 24 h. PCA of gene expression dataset from six independent samples (denoted as colored spheres) of cardiac myocytes treated with TSA for 6 or 24 h shows unique locations of each treatment cohort (top panel). The transcriptomic data sets were filtered for significant differential expression based on Illumina detection values (> 0.99 for all samples for at least one group), fold change in treatment versus control group (>2.0 fold), ANOVA p-values (<0.05) and t-test p-values (<0.05) to identify DEGs that were arranged by unsupervised hierarchical clustering (bottom).

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