Sequence Name | Gene name | Description | Organism | Disease model | Expression in neurons |
---|---|---|---|---|---|
Y53C10A.12 | hsf-1 | Heat-shock transcription factor | worm | Aβ, P, S, SOD, T | yes |
F26D10.3 | hsp-1 | HSP70 protein family | fly, worm | P, T, S | yes |
F54D5.8 | dnj-13 | Molecular chaperone (DnaJ) | fly | P, T | ? |
K01C8.10 | cct-4 | Chaperone containing TCP-1 | worm | P, SOD | yes |
C07G2.3 | cct-5 | Chaperone containing TCP-1 | worm | P, SOD | ? |
T09B4.10 | chn-1 | C-term of HSP-70 interacting protein (E3 ubiquitin ligase) | fly, worm | P, T | yes |
Y94H6A.6 | ubc-8 | Ubiquitin conjugating enzyme | fly, yeast | P, S | ? |
M7.1 | let-70 | E2 Ubiquitin conjugating enzyme | fly | P | yes |
C06A1.1 | cdc-48.1 | AAA ATPase, functions as a ubiquitin-related chaperone | worm | P | Yes |
F52D10.3, M117.2 | ftt-2, par-5 | 14-3-3 family | fly | P | yes |
C39F7.4 | rab-1 | Small Ras-like GTPase Rab1 | fly, yeast, worm | P, S | yes |
B0361.10 | ykt-6 | SNARE protein YKT6 | yeast | S | ? |
C54H2.5 | sft-4 | SURF-4 related to cargo transport protein ERV29 | worm, yeast | S | yes |
Y54E2A.12 | tbc-20 | Predicted GTPase activator protein | yeast | S | ? |
R11A8.4 | sir-2.1 | NAD-dependent histone deacetylase | fly, worm | P, S | Yes |
C53A5.3 | hda-1 | Histone deacetylase 1 | fly, worm | P, S | No? |
F02E9.4 | sin-3 | SIN3 family of histone deacetylase subunits | fly | P, S | yes |
F59F4.1 | - | Acyl-CoA oxidase | fly, yeast, worm | P, S, T | ? |
ZK256.1a | pmr-1 | Golgi P-type ATPase Ca2+ -pump | yeast | S | yes |
W08D2.5, | catp-6 | Predicted lysosomal P-type ATPase | worm, yeast | S | ? |
Y43F4B.4 | npp-18 | Nuclear pore complex protein | fly | P | yes |
F49E10.5 | ctbp-1 | Transcriptional co-repressor homolog | fly | P | ? |
K08F8.6 | let-19 | Transcriptional cofactor | fly | P | yes |
T17E9.1 | kin-18 | Serine-threonine protein kinase | fly, worm | P, T | yes |
H18N23.2 | - | Protein phosphatase, regulatory subunit PPP1R3C/D | fly, worm | P, SOD | ? |
T14F9.1 | vha-15 (phi-52) | Vacuolar ATPase subunit H | worm | P, S | Yes |
T21E12.4 | dhc-1 | Dynein heavy chain | fly, worm | P | Yes |
Y113G7B.18 | mdt-17 | MeDiaTor | worm | S, SOD | ? |
Y116A8C.35 | uaf-2 | U2AF splicing factor | worm | P, S | Yes |
F56C11.1 | bli-3 | Homologue of dual oxidase | worm | P, SOD | No |
C32E8.10c | unc-11 | Clathrin-adaptor protein AP180 | worm, yeast | Aβ, P | Yes |
JC8.10b | unc-26 | Synaptojanin | worm, yeast | Aβ, P | Yes |
ZK742.1a | xpo-1 | Exportin-1 | Fly, yeast | Aβ, P | ? |
C05C8.7 | phi-49 | Mannose-6-phosphate isomerase | worm | P, SOD | No |