Table 3 Biological processes associated with the identified overlapping genetic regulators of neurodegeneration.
Biological process | Genes |
|---|---|
Heat shock transcription factor | hsf-1 |
Molecular chaperones | hsp-1, dnj-13, cct-4, cct-5 |
Ubiquitin related | chn-1, ubc-8, let-70, cdc-48.1 |
Histone deacetylases | sir2.1, had-1, sin-3 |
Signalling/chaperone | fft-2/par-5 |
Transcriptional cofactor/regulator | ctbp-1, let-19, mdt-17, uaf-2 |
Nucleopore/nuclear export | npp-18, xpo-1 |
Vesicular transport | rab-1, sft-4, tbc-20, ykt-6, dhc-1 |
Endocytosis | unc-11, unc-26 |
Transport ATPase | catp-6, pmr-1, vha-15 |
Protein phosphorylation | kin-18, H18N13.2 |
Other cellular processes | bli-3, phi-49, F59F4.1 |