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Table 2 Genes identified on chromosome 2 that possibly alter obesity risk

From: An integrated approach of comparative genomics and heritability analysis of pig and human on obesity trait: evidence for candidate genes on human chromosome 2

Genes variantsa Positiona p-value Function Related Diseases Reference
MRPL33 DBWU0000918 118300227(3) 0.008089 Mammalian mitochondrial ribosomal proteins Type 2 Diabetes Mellitus [29, 31]
  rs4666014 28019175 0.002452    
STK39 MARC0089023 72257469(3) 0.000199 Serine/threonine kinase Hyper-tension [3234]
  rs10497337 169027149 0.008838    
ZNF385B ALGA0088337 94656675(15) 0.009191 zinc finger protein Sudden cardiac arrest [35]
  rs17824619 180608843 0.002138    
PARD3B MARC0060764 109267583(3) 0.005037 cell cycle/cell division Type 2 Diabetes, chronic kidney disease [36]
  rs7568370 205899090 0.000275    
  rs1510772 205934654 0.001348    
  rs4675490 205942560 0.000644    
ERBB4 DRGA0015447 126154685(15) 0.003372 Tyr protein kinase Diabetes [37]
  ALGA0086849 126191456(15) 0.006382    
  rs16848144 213141299 0.008011    
  1. a rs denotes human markers b syntenic pig chromosome in parentheses.