An integrated approach of comparative genomics and heritability analysis of pig and human on obesity trait: evidence for candidate genes on human chromosome 2

Table 2 Genes identified on chromosome 2 that possibly alter obesity risk

Genes	variants^a	Position^a	p-value	Function	Related Diseases	Reference
MRPL33	DBWU0000918	118300227(3)	0.008089	Mammalian mitochondrial ribosomal proteins	Type 2 Diabetes Mellitus	[29, 31]
	rs4666014	28019175	0.002452
STK39	MARC0089023	72257469(3)	0.000199	Serine/threonine kinase	Hyper-tension	[32–34]
	rs10497337	169027149	0.008838
ZNF385B	ALGA0088337	94656675(15)	0.009191	zinc finger protein	Sudden cardiac arrest	[35]
	rs17824619	180608843	0.002138
PARD3B	MARC0060764	109267583(3)	0.005037	cell cycle/cell division	Type 2 Diabetes, chronic kidney disease	[36]
	rs7568370	205899090	0.000275
	rs1510772	205934654	0.001348
	rs4675490	205942560	0.000644
ERBB4	DRGA0015447	126154685(15)	0.003372	Tyr protein kinase	Diabetes	[37]
	ALGA0086849	126191456(15)	0.006382
	rs16848144	213141299	0.008011

ISSN: 1471-2164