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Figure 2 | BMC Genomics

Figure 2

From: Genomic insights of protein arginine methyltransferase Hmt1 binding reveals novel regulatory functions

Figure 2

Hmt1-binding sites are enriched at ORF genes. A) Average Hmt1 enrichment profiles for all ORFs bound (“ALL ORFs), ORFs with high- (“≥ 15 mRNA/hr”), medium- (“1-15 mRNA/hr”), and low- (“ ≤ 1 mRNA/hr”) transcriptional frequencies. B) Histone enrichment/depletion calculations of promoters and genes for Hmt1-bound ORFs from ChromatinDB. C) Directed ChIP to assess the role of Hmt1 on the levels of pan-H4ac and H3K36me2. Representative ORFs bound-by Hmt1 were assayed for the level of the specified histone modification in WT and hmt1- null cells.

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