Table 3 Highly Expressed SAE-enriched Transcription Factors1
From: RNA-Seq quantification of the human small airway epithelium transcriptome
Category | Gene symbol | Gene title | Median expression level (RPKM) |
|---|---|---|---|
Basic helix-loop -helix | ATF6B | activating transcription factor 6 beta | 26.4 |
| Â | BHLHE40 | basic helix-loop-helix family, member e40 | 16.2 |
| Â | RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 15.6 |
| Â | HES6 | hairy and enhancer of split 6 (Drosophila) | 13.6 |
| Â | FOXC1 | forkhead box C1 | 9.3 |
| Â | CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 9.1 |
| Â | HEY1 | hairy/enhancer-of-split related with YRPW motif 1 | 9.1 |
Zinc finger | TRIM29 | tripartite motif-containing 29 | 77.3 |
| Â | KLF5 | kruppel-like factor 5 (intestinal) | 42.0 |
| Â | RREB1 | ras responsive element binding protein 1 | 7.2 |
| Â | KLF4 | kruppel-like factor 4 (gut) | 7.1 |
Helix-turn-helix | FOXJ1 | forkhead box J1 | 363.1 |
| Â | ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific) | 170.1 |
| Â | FOXA1 | forkhead box A1 | 62.6 |
| Â | EHF | ets homologous factor | 39.1 |
| Â | TBX1 | T-box 1 | 19.7 |
| Â | SATB1 | SATB homeobox 1 | 19.3 |
| Â | MYB | v-myb myeloblastosis viral oncogene homolog (avian) | 15.9 |
| Â | SIX2 | SIX homeobox 2 | 13.9 |
| Â | NKX2-1 | NK2 homeobox 1 | 11.6 |
| Â | PHTF1 | putative homeodomain transcription factor 1 | 10.9 |
| Â | TEAD3 | TEA domain family member 3 | 10.9 |
| Â | ETV6 | ets variant 6 | 10.6 |
| Â | FOXA2 | forkhead box A2 | 6.9 |
β-scaffold | SOX2 | SRY (sex determining region Y)-box 2 | 71.3 |
| Â | RUNX1 | runt-related transcription factor 1 | 16.7 |
| Â | SOX4 | SRY (sex determining region Y)-box 4 | 11.4 |
| Â | TFCP2 | transcription factor CP2 | 10.7 |
| Â | SOX21 | SRY (sex determining region Y)-box 21 | 9.0 |
| Â | NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 | 7.8 |
| Â | SOX9 | SRY (sex determining region Y)-box 9 | 7.7 |