Table 4 Highly Expressed SAE-enriched Transmembrane Receptors1
From: RNA-Seq quantification of the human small airway epithelium transcriptome
Category | Gene symbol | Gene title | Median expression level (RPKM) |
|---|---|---|---|
G protein coupled/7 transmembrane | CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila) | 63.0 |
| Â | C5AR1 | complement component 5a receptor 1 | 27.6 |
| Â | GPR110 | G protein-coupled receptor 110 | 21.7 |
| Â | GPRC5C | G protein-coupled receptor, family C, group 5, member C | 20.3 |
| Â | OXTR | oxytocin receptor | 19.3 |
| Â | LPAR3 | lysophosphatidic acid receptor 3 | 17.6 |
| Â | FZD6 | frizzled homolog 6 (Drosophila) | 12.5 |
| Â | PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 9.2 |
| Â | VIPR1 | vasoactive intestinal peptide receptor 1 | 8.8 |
| Â | ADRB1 | adrenergic, beta-1-, receptor | 7.8 |
| Â | GPR116 | G protein-coupled receptor 116 | 7.5 |
| Â | FZD8 | frizzled homolog 8 (Drosophila) | 7.1 |
| Â | ADRA2A | adrenergic, alpha-2A-, receptor | 6.8 |
| Â | PTGFR | prostaglandin F receptor (FP) | 6.6 |
Cyclase related | NRP2 | neuropilin 2 | 12.0 |
| Â | NPR2 | natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B) | 10.7 |
| Â | CRCP | CGRP receptor component | 10.4 |
IgG like | SCARA3 | scavenger receptor class A, member 3 | 21.8 |
| Â | PTPRT | protein tyrosine phosphatase, receptor type, T | 13.0 |
| Â | IL1R1 | interleukin 1 receptor, type I | 6.5 |
Ion channel | GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 15.7 |
Serine kinase | TGFBR2 | transforming growth factor, beta receptor II (70/80 kDa) | 8.8 |
Tyrosine kinase | DDR1 | discoidin domain receptor tyrosine kinase 1 | 140.3 |
| Â | FGFR3 | fibroblast growth factor receptor 3 | 19.9 |
| Â | IGF1R | insulin-like growth factor 1 receptor | 15.2 |
| Â | PTK7 | PTK7 protein tyrosine kinase 7 | 14.5 |
| Â | FGFR2 | fibroblast growth factor receptor 2 | 11.6 |
| Â | MET | met proto-oncogene (hepatocyte growth factor receptor) | 8.5 |
| Â | EGFR | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 7.2 |
Other | SORL1 | sortilin-related receptor, L(DLR class) A repeats-containing | 7.7 |