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Table 3 Effect of a chronic Western diet on the expression of genes related to cholesterol metabolism in the livera

From: C57Bl/6 N mice on a western diet display reduced intestinal and hepatic cholesterol levels despite a plasma hypercholesterolemia

Symbol Gene name FC p-value
Cyp51 Cytochrome P450, family 51 1.80 ± 0.28 0.056
Dhcr7 7-dehydrocholesterol reductase 1.72 ± 0.23 0.025
Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase 2.23 ± 0.48 0.033
Pmvk Phosphomevalonate kinase 1.22 ± 0.16 0.378
Srebp-2 Sterol regulatory element binding factor 2 1.37 ± 0.08 0.009
  1. a Abbreviations: FC fold change (Western diet vs. control)