Figure 5

Polymorphisms among M. avium complex (MAC) members. (A) Table of the total single nucleotide polymorphisms (SNPs) present in each genome. (B) Phylogenetic relationship among MAC strains using all SNPs or those restricted to coding regions (C). The trees were constructed using the Neighbor-Joining method [38]. Each tree is drawn to scale, with branch lengths (indicated below the branches) in the same units as those of the evolutionary distances used to infer the phylogenetic tree. The evolutionary distances were computed using the LogDet (Tamura-Kumar) method [39] and are in the units of the number of base substitutions per site. There were a total of 50,924 SNPs in the dataset for (B) and 38,546 SNPs in (C). Evolutionary analyses were conducted in MEGA5 [40].