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Figure 3 | BMC Genomics

Figure 3

From: Sequence signatures involved in targeting the male-specific lethal complex to X-chromosomal genes in Drosophila melanogaster

Figure 3

Results from promoters of MSL-bound genes. Results based on OPLS-DA of promoter sequences of genes expressed and strongly or weakly bound by MSL complex on chromosome X. (A) Promoter motif built from top sequences words. (B) Fraction of genes strongly and weakly bound by MSL as well as expressed genes on chromosome 2L with the promoter motif and BEAF-32 binding within 500 bp of the TSS. (C) Fraction of all expressed genes on the X-chromosome with the promoter motif (red) or BEAF-32 binding (green) within 500 bp of TSS grouped by average MSL enrichment (average of MSL-1, MSL-3 and MOF gene binding values). Note that a weakly bound gene in the initial model was a gene that had gene binding values for all the three proteins lower than 0.5. 90% of these genes fall into the classes with average MSL enrichment less than 0.4. The average MSL enrichment for the weakly bound class is 0.24

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