Skip to main content

Table 2 Number of mutations in each of the groups in which UniProt divides the protein kinase superfamily

From: Prioritization of pathogenic mutations in the protein kinase superfamily

Group Disease Neutral Total
TK † 496 565 1061
TKL † 172 151 323
Atypical_PI3-PI4 † 49 138 187
CAMK † 40 518 558
Other 36 411 447
RGC † 23 35 58
CMGC † 18 178 196
AGC † 16 190 206
STE 7 222 229
Atypical_ADCK 6 14 20
Atypical_Alpha-type 1 88 89
CK1 1 52 53
NEK 0 45 45
Atypical_RIO 0 14 14
Atypical_PDK-BCKDK 0 5 5
Atypical_FAST 0 1 1
  1. Number of mutations in each of the groups in which UniProt divides the protein kinase superfamily. The groups enriched in disease-associated mutations are highlighted by †.