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Table 4 Most discriminative GO annotations

From: Predicting cancer-associated germline variations in proteins

GO-term

Description

Cellular Component ( C )

 

GO:0032301

MutSalpha complex

GO:0032300

Mismatch repair complex

GO:0032302

MutSbeta complex

GO:0005773

Vacuole

GO:0005764

Lysosome

GO:0000323

Lytic vacuole

GO:0030877

Beta-catenin destruction complex

GO:0016328

Lateral plasma membrane

GO:0034747

Axin-APC-beta-catenin-GSK3B complex

Molecular Function ( F )

 

GO:0030983

Mismatched DNA binding

GO:0032137

Guanine/thymine mispair binding

GO:0032134

Mispaired DNA binding

GO:0030291

Protein serine/threonine kinase inhibitor activity

GO:0016538

Cyclin-dependent protein kinase regulator activity

GO:0004861

Cyclin-dependent protein kinase inhibitor activity

GO:0019887

Protein kinase regulator activity

GO:0019207

Kinase regulator activity

GO:0005099

Ras GTPase activator activity

Biological Process ( P )

 

GO:0006298

Mismatch repair

GO:0044271

Cellular nitrogen compound biosynthetic process

GO:0006301

Postreplication repair

GO:0046395

Carboxylic acid catabolic process

GO:0016054

Organic acid catabolic process

GO:0009310

Amine catabolic process

GO:0070507

Regulation of microtubule cytoskeleton organization

GO:0032886

Regulation of microtubule-based process

GO:0009063

Cellular amino acid catabolic process.