Figure 3

Combined view of GE and CN alterations obtained for the GBM dataset. The regions for all the human chromosomes (chr) that are altered either in CN or in GE are presented along the whole genome keeping the proportional size of the chromosomes. The graph shows the frequency of such alterations in the GBM samples. The colors correspond to GE up-regulated regions (in red) or down-regulated regions (in green), and -plotted on top- the CN gains (in pale red) or the CN losses (in pale green). Blue lines mark the regions that change in more than 25% of the GBM patients. The chromosomes with most significant changes (that present large regions included in the categories U-G or D-L) are labeled: U-G chr 7, chr 19, chr 20; D-L chr 10, chr 13, chr 22.