Table 5 Performance for optimizing the combination of four drugs in the presence of noise.
|  | Noise level | Search type | Performance metric | Gur Game (simultaneous) | Gur Game (sequential) | Previous search algorithm[11](α= 1) | ARU algorithm (proposed) (α= 1) |
|---|---|---|---|---|---|---|---|
f4a(x) | (2%) | A | success rate unique comb. | 21% | 13% | 96% | 98% |
| Â | Â | Â | Â | 798.9 | 711.7 | 393.9 | 327.4 |
| Â | Â | B | success rate iterations | 21% | 12% | 96% | 97% |
| Â | Â | Â | Â | 941.9 | 1032.1 | 558.3 | 452.3 |
| Â | (5%) | A | success rate unique comb. | 21% | 14% | 90% | 95% |
| Â | Â | Â | Â | 816.3 | 653.6 | 473.1 | 398.3 |
| Â | Â | B | success rate iterations | 21% | 13% | 90% | 95% |
| Â | Â | Â | Â | 895.6 | 1022.9 | 675.4 | 581.2 |
| Â | (8%) | A | success rate unique comb. | 24% | 14% | 85% | 95% |
| Â | Â | Â | Â | 858.7 | 681.6 | 505.7 | 433.6 |
| Â | Â | B | success rate iterations | 23% | 13% | 84% | 92% |
| Â | Â | Â | Â | 997.1 | 1008.9 | 720.8 | 648.5 |
f4b(x) | (2%) | A | success rate unique comb. | 62% | 41% | 100% | 100% |
| Â | Â | Â | Â | 634.5 | 523.1 | 138.0 | 103.1 |
| Â | Â | B | success rate iterations | 51% | 26% | 100% | 100% |
| Â | Â | Â | Â | 932.4 | 903.0 | 236.9 | 182.8 |
| Â | (5%) | A | success rate unique comb. | 75% | 68% | 100% | 100% |
| Â | Â | Â | Â | 610..2 | 468.0 | 231.1 | 150.9 |
| Â | Â | B | success rate iterations | 50% | 25% | 100% | 100% |
| Â | Â | Â | Â | 855.9 | 921.2 | 411.0 | 258.8 |
| Â | (8%) | A | success rate unique comb. | 86% | 82% | 98% | 100% |
| Â | Â | Â | Â | 525.8 | 430.1 | 314.2 | 215.9 |
| Â | Â | B | success rate iterations | 50% | 24% | 94% | 100% |
| Â | Â | Â | Â | 835.3 | 979.2 | 602.0 | 393.8 |