Steps for combining three types of p -values. For a selected GO category and a miRNA-gene target-pair variation, for each GO term, three p-values are computed for ρ, τ, and μ, and then rank normalized. S
(n) denotes the set of GO terms whose p-values' ranks in the ρ hypergeometric distribution are less than or equal to n. By applying set operations, four combinations of S
(n) are created for further evaluation.