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Table 4 Comparison of clinical characteristics between predicted subgroups of venous metastasis

From: Differential combinatorial regulatory network analysis related to venous metastasis of hepatocellular carcinoma

  Predicted NM Predicted M P value
Patient cohort (n = 198) n = 137 n = 61  
Gender(male/female) 121/16 53/8 0.9601
Age(yr, mean ± SD) 49.99 ± 11.22 50.15 ± 9.54 0.8235
Number of nodule(1/2/3/4) 117/18/2 55/4/1/1 0.2603
Tumor capsule(complete/none) 53/84 24/37 0.9441
Cirrhosis(no/yes) 8/129 5/56 0.7584
AFP(log2-transformed, mean ± SD) 6.79 ± 3.96 8.08 ± 4.56 0.0395
TB(μmol/L, median(25-75%)) 15.4(12.1-20.2) 17.4(11.4-22.1) 0.2954
ALT(μ/L, median(25-75%)) 43(31-61) 49(32-66) 0.3929
OKUDA stage(0/1) 119/18 49/12 0.3325
CLIP stage(0/1/2/3/4) 64/49/22/1/1 28/15/12/4/2 0.0509
BCLC stage(0/A/B/C) 15/103/14/5 7/35/7/12 0.0022
TNM stage(I/II/III) 65/57/15 23/23/15 0.0441
Child-Pugh class(A/B) 132/5 57/4 0.5910
  1. P value: Comparison between clinic pathological indicators of non-metastatic and metastatic groups was conducted using chi-square test for discrete variables and Wilcoxon test for continuous variables.