Figure 1
From: CTF: a CRF-based transcription factor binding sites finding system
System diagram of CTF. This figure showed the system diagram of CTF. Different features (PWM, chromatin signatures, and any other features such as the distance to a TSS) were integrated into CTF. Combining these features, CTF called CRF framework to obtain the probability-like scores of TFBSs across the whole genome. The CRF model of CTF contained two states: transcription factor binding site (TFBS) state and non-TFBS (background) state.