From: Identifying the status of genetic lesions in cancer clinical trial documents using machine learning
Category | Definition | Examples | ||
---|---|---|---|---|
ID | Stage I | Stage II | Â | Â |
1 | Gene-related | Genetic lesion detected | Genetic lesion status is detected. | • Positive EGFR mutation test... • Patient with EGFR positive ... |
2 |  | Genetic lesion not detected | Genetic lesion status is Not Detected. | • ...negative staining for Kit. • Patient must have wild type KRAS. |
3 |  | Genetic lesion mentioned | Analysis of genetic lesion is mentioned but not particular results | • BRAF - gene analysis of archival tissue • mutational analysis of genes such as EGFR ... |
4 |  | Gene only | It refers to the gene entity only, no status is associated. | • KIT is a gene that codes for ... • WT1 is a protein in cancer cells that regulates gene expression and ... |
5 | Drug |  | Gene related drugs, drug classes, or other therapy | • WT1 Peptide Vaccination in Carcinomas. • Prior treatment with EGFR inhibitor chemotherapy... |
6 | Others |  | None of the above classes, e.g., English words, | • ...using the kit and testing procedures. • Criteria are met. |