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Table 1 Literature based functional significance (LBFS) of gene sets generated by four statistical tests for three different microarray experiments.

From: Literature aided determination of data quality and statistical significance threshold for gene expression studies

  

LCI

  

LBFS

 

Gene list

PGC-1beta

IL2

ET1

PGC-1beta

IL2

ET1

Welch t-Test

0.34

0.34

0.17

7.08E-06

0.0004

0.45

Mann-Whitney

0.2

0.2

0.13

0.118

0.0075

1

Student t-Test

0.38

0.38

0.1

1.24E-07

0.071

1

Empirical Bayes

0.4

0.19

0.05

1.36E-08

0.11

1

  1. For comparison the Literature Cohesion Index (LCI) which is used to calculate LBFS is displayed for each experiment.
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BMC Genomics

ISSN: 1471-2164

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