TY - JOUR AU - Harwich, Michael D. AU - Serrano, Myrna G. AU - Fettweis, Jennifer M. AU - Alves, João MP AU - Reimers, Mark A. AU - Buck, Gregory A. AU - Jefferson, Kimberly K. AU - Vaginal Microbiome Consortium (additional members) PY - 2012 DA - 2012/12/17 TI - Genomic sequence analysis and characterization of Sneathia amnii sp. nov JO - BMC Genomics SP - S4 VL - 13 IS - 8 AB - Bacteria of the genus Sneathia are emerging as potential pathogens of the female reproductive tract. Species of Sneathia, which were formerly grouped with Leptotrichia, can be part of the normal microbiota of the genitourinary tracts of men and women, but they are also associated with a variety of clinical conditions including bacterial vaginosis, preeclampsia, preterm labor, spontaneous abortion, post-partum bacteremia and other invasive infections. Sneathia species also exhibit a significant correlation with sexually transmitted diseases and cervical cancer. Because Sneathia species are fastidious and rarely cultured successfully in vitro; and the genomes of members of the genus had until now not been characterized, very little is known about the physiology or the virulence of these organisms. SN - 1471-2164 UR - https://doi.org/10.1186/1471-2164-13-S8-S4 DO - 10.1186/1471-2164-13-S8-S4 ID - Harwich2012 ER -