Comparative genomics using teleost fish helps to systematically identify target gene bodies of functionally defined human enhancers

Table 3 List of transcription factors having over-representative occurrence in brain specific cis -acting sites

Transcription factor	Protein-related information	Known endogenous expression pattern	Source
AML1	RUNT-type transcription factor	spinal cord, hindbrain	[29, 30]
ARNT	Helix-loop-helix DNA-binding	spinal cord, forebrain, midbrain, hindbrain	[31, 32]
cFOS	Basic-leucine zipper (bZIP) transcription factor	hindbrain	[33, 34]
c-REL	Immunoglobulin-like fold	CNS (components not defined yet)	[35, 36]
FREAC	Winged helix-turn-helix transcription repressor	CNS (components not defined yet)	[37, 38]
HFH	Winged helix-turn-helix transcription repressor DNA	CNS (components not defined yet)	[39, 40]
HNF3B	Winged helix-turn-helix transcription repressor DNA	Spinal-cord, forebrain midbrain, hindbrain	[41, 42]
MEF2	myocyte-specific enhancer factor 2A	forebrain, hindbrain	[43, 44]
NF-KappaB	Immunoglobulin-like fold	spinal cord, forebrain, midbrain, hindbrain	[45, 46]
nMYC	Helix-loop-helix DNA-binding	spinal cord, forebrain, midbrain, hindbrain	[47, 48]
SOX17	High mobility group, HMG1/HMG2	spinal cord, forebrain, midbrain, hindbrain	[49]
SOX5	High mobility group, HMG1/HMG2	spinal cord, hindbrain, midbrain	[50, 51]
Talbeta-E47S	Helix-loop-helix DNA-binding	spinal cord, forebrain, midbrain, hindbrain	[52, 53]
USF	Helix-loop-helix DNA-binding	spinal cord, forebrain, hindbrain	[38, 54]

This table also provides references of literature (last column) that addresses the type/function and endogenous expression pattern of transcription factors.

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