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Table 1 List of CNVs identified via WGS and Sanger resequencing

From: The mutation rate of mycobacterial repetitive unit loci in strains of M. tuberculosisfrom cynomolgus macaque infection

MIRU locus

Read depth candidate strains

Mate pair candidate strains

Copy numbers

154-A

None

None

1

154-B

None

None

2

424

None

None

2

577

None

None

2

580

A-3

None

3

802

H-3

H-3

3; (H-3 = 4)

960-A

I-2

None

3

960-B

None

None

1

1644

None

None

3

1955-A

None

None

1

1955-B

None

None

1

2059

None

None

1

2163b

None

None

3

2165*

None

None

3

2347

None

None

1

2401-A

None

None

3

2401-B

None

None

1

2461

None

None

2

2531-A

None

None

1

2531-B

None

None

1

2687-A

None

None

1

2687-B

None

None

1

2996

None

C-1

5

3007

None

None

3

3171*

None

None

2

3192

G-3

C-1

2; (G-3 = 1)

3690

None

C-1

5

4052

None

None

3

4156

None

None

3

4348

None

None

2

  1. Loci containing asterisks (2165 and 3171) were only analyzed using Sanger sequencing. Bolded strains (H-3 at locus 802 and G-3 at locus 3192) were confirmed insertion and deletion events, respectively, via Sanger resequencing. Discrete copy numbers for each strain were determined by Sanger sequencing. Previous strain notation is used [17].