(A) Alignments of the N-terminal clip-domains of N. lugens CLIPs. (B) The C-terminal serine protease domains of N. lugens CLIPs. The CLUSTALW program was used for alignments. The gray shades indicate the conserved cysteine residues and active triad (His, Asp and Ser). The predicted disulfide linkages between conserved cysteines are shown by lines. The possible proteolytic cleavage site is indicated with an arrowhead [42, 45].