Figure 3

Venn diagram of human disease genes orthologs and the relationship between lipid genes and metabolic disease associated genes. A: Venn diagram of 15181 human disease gene orthologs made with VENNY. Numbers in the overlapping and non-overlapping areas of the diagram indicate the number of genes found by overlapping or unique sets of orthologs in each species; B: Venn diagram of 1264 human metabolic disease genes orthologs; C: Comparison of 581 human lipid genes with human metabolic disease genes (97 of 581 lipid genes overlapped with metabolic disease genes); D: Similarly to the phenomenon in human genes, 94 of 471 C. elegans lipid genes were related to metabolic disease; E: In C. Elegans, 327 lipid genes were associated with human diseases.