Gene symbol | Gene name | 0/ctrl | +2/ctrl | Mice L2/P7 |
---|---|---|---|---|
Triglyceride synthesis | ||||
Gyk | Glycerol kinase | 1.49 | 1.92 | 1.26 |
Gpd1 | Glycerol 3-PO4 dehydrogenase (cytosolic) | −1.50 | −2.08 | 2.25 |
Acsl1 | Long-chain Acyl-CoA synthetase 1 | 1.80 | 2.94 | 1.51 |
Acsl4 | Long-chain-fatty-acid-CoA ligase 4 | ns | −2.42 | −1.35 |
Gpam; GPAT | Glycerol-3-phosphate acyltransferase | ns | 2.03 | −1.22 |
Agpat3 | 1-acylglycerol-3-phosphate O-acyltransferase 3* | ns | 1.52 | Na |
Agpat9 | 1-acylglycerol-3-phosphate O-acyltransferase 9* | ns | 2.38 | Na |
Dgat2 | Diacylglycerol O-acyltransferase 2* | 1.61 | 3.66 | Na |
Fatty acid plasma membrane transporters | ||||
Slc27a1 | Fatty acid transporter, member 1 | −2.21 | −2.21 | −1.01 |
Slc27a4 | Fatty acid transporter, member 4 | ns | 2.01 | 1.99 |
Cd36 | Fatty acid translocase | 2.69 | 5.57 | 1.08 |
Fatty acid binding proteins | ||||
Fabp3 | Fatty acid binding protein 3, muscle and heart | −3.17 | −4.88 | −1.02 |
Fabp5 | Fatty acid binding protein 5 | ns | 2.92 | 1.31 |
Fatty acid degradation | ||||
Lpl | Lipoprotein lipase | 1.66 | 2.08 | 1.24 |
Cte1 | Cytosolic acyl coenzyme A thioester hydrolase | ns | 1.59 | −16.66 |
Crat | Carnitine acetyltransferase IA | ns | 1.35 | Na |
Crat | Carnitine acetyltransferase IB | ns | −2.02 | na |
Cpt2; CPTII | Carnitine acetyltransferase II | ns | 1.43 | −2.56 |
Ech1 | Enoyl coenzyme A hydratase 1, peroxisomal | ns | 1.69 | −2.08 |
Hadhsc | L-3-hydroxyacyl-Coenzyme A dehydrogenase | ns | 1.49 | −1.20 |
LOC231086 | Betaketothiolase | ns | 1.23 | −1.56 |
Fatty acid synthesis | ||||
Acly | ATP citrate lyase | 1.46 | 1.88 | 2.66 |
Mdh1 | Malate dehydrogenase, cytosolic | 1.19 | 1.23 | 1.07 |
Mod1 | Malic enzyme, cytosolic | 1.41 | 2.17 | 1.54 |
ACC | Acetyl CoA carboxylase | 1.68 | 2.26 | Na |
Fasn | Fatty acid synthase | 1.60 | 2.46 | 1.65 |
Scd1 | Stearoyl-Coenzyme A desaturase 1 | ns | 2.00 | 1.55^ |
Scd5 | Stearoyl-Coenzyme A desaturase 5* | −1.45 | −1.48 | Na |
Fads1 | Fatty acid desaturase 1 | ns | −2.22 | 2.40 |
Elovl4 | Elongation of very long chain fatty acids 4* | ns | −7.28 | Na |
Elovl5 | Elongation of very long chain fatty acids 5* | ns | −2.05 | Na |
Elovl6 | Elongation of very long chain fatty acids 6* | 1.32 | 1.63 | Na |
Thrsp; Lpgp | Spot 14, thyroid hormone-inducible hepatic protein | ns | −4.90 | 1.89 |