Neighbor-joining consensus trees of the four P450 clans. (A) CYP2; (B) mitochondrial; (C) CYP3; and (D) CYP4. The phylogenetic trees were generated by MEGA 5 using the amino acid sequences from T. castaneum (Tc), D . melanogaster (Dm), A. gambiae (Ag), and A. mellifera (Am). Two-letter species designations followed the specific gene names. All nodes have significant bootstrap support based on 2,000 replicates. The trees were created with cut-off value of 50%.