Figure 4From: miRConnect 2.0: identification of oncogenic, antagonistic miRNA families in three human cancersAgonistic and antagonistic miRNAs and their correlating oncogenic gene signatures in three primary cancers. (A) Correlation network between agonistic miRNAs (blue), antagonistic miRNAs (dark green), and 6 oncogenic signatures (light green) shared by OvCa, GBM, and KIRC. (B) Tumor/normal log2 ratio of miRNA expression in primary cancers. From left to right: agonists, antagonists, and EMT regulators. miR-21 is included as a positive control as a miRNA that is upregulated in most human cancers. Stippled lines indicate the 1.5 fold up- or downregulation, taken as the cut-off for genes deregulated in the cancers when compared to matched normal tissues.Back to article page