Extensive circadian and light regulation of the transcriptome in the malaria mosquito Anopheles gambiae

BMC Genomics

Table 1 Comparing rhythmic An. gambiae genes to Ae. aegypti rhythmic genes

Category	Rhythmic Anophelesgenes	Aedeshomologues	Rhythmic Aedeshomologues
Chromatin Modification	19	17	8
Detoxification	38	35	18
Immunity	47	40	25
Metabolism	222	207	99
Neuronal/Behavior	43	39	16
Olfaction	29	28	8
Other	106	103	39
Protein Folding/Modification	43	39	21
Proteolysis	47	42	16
Redox	54	51	24
Signal Transduction	79	72	29
Structural	47	43	18
Transcription	68	63	30
Translation	49	46	15
Transport	123	46	49
Unknown	373	319	120
Vision	13	12	4
Totals:	1400	1202	539

The list of An. gambiae genes found rhythmic in An. gambiae heads under LD conditions from reanalyzed Rund et al. 2011 data [30] with a JTK_CYCLE q < 0.05 cutoff are compared to Ae. aegypti heads under LD conditions from Ptitsyn et al. 2011 [34] data also reanalyzed with JTK_CYCLE q < 0.05 cutoff. For each biological functional category, the number of genes found rhythmic in An. gambiae, the number of those genes where a homologue was identified in Ae. aegypti, and finally the number of those homologues that were found rhythmic in Ae. aegypti is provided.

ISSN: 1471-2164