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Table 1 Biological interpretation of the 34 clusters obtained from discrete transition profiles

From: Transcriptional and epigenetic signatures of zygotic genome activation during early drosophila embryogenesis

Experiment

Profiles

Nucleo-cytoplasmic ratio NC

Gene number

Biological interpretation

Pilot

ddss

 

35

 

Lu

d d D d d H

NC

41

Maternal mRNA degraded during cellularisation

Lu

d d D d s H

Maternal clock

165

 

Pilot

dsss

 

885

 

Lu

d s D d s H

NC

37

Maternal mRNA degraded during slow phase of cellularisation

Lu

d s D s s H

Maternal clock

406

 

Pilot

dssu

 

11

Maternal mRNA degraded during slow phase of cellularisation

    

and zygotic mRNAs transcription during late phase of gastrulation

Lu

d s D s u H

Maternal clock

163

 

Pilot

dsus

 

13

Maternal mRNA degraded during slow phase of cellularisation and zygotic mRNAs transcription during early phase of gastrulation

Pilot

duss

 

66

Maternal mRNA degraded during slow phase of cellularisation and zygotic mRNAs transcription during fast phase of cellularisation

Pilot

sdds

 

23

 

Lu

s d D s d H

NC

91

 

Lu

s d D d d H

Maternal clock

61

Maternal mRNA degraded from fast phase of cellularisation

Lu

s d D d s H

Maternal clock

97

 

Pilot

sdss

 

415

 

Pilot

ssdd

 

12

 

Lu

s s D s d H

Horloge maternelle

111

Maternal mRNA degraded from early phase of gastrulation

Pilot

ssds

 

22

 

Pilot

sssd

 

77

Maternal mRNA degraded from late phase of gastrulation

Pilot

sssu

 

28

Zygotic mRNAs transcription during late phase of gastrulation

Pilot

ssus

 

21

Zygotic mRNAs transcription during early phase of gastrulation

Lu

s s D s u H

Maternal clock

164

 

Pilot

suss

 

75

Zygotic mRNAs transcription during fast phase of cellularisation

Pilot

suus

 

11

 

Lu

s u D s u H

NC

154

 

Lu

s u D u u H

Maternal clock

47

 

Pilot

udss*

 

23

Transient zygotic mRNAs transcription during cellularisation

Pilot

ussd*

 

16

 

Pilot

usss*

 

87

 

Pilot

uuss*

 

23

 

Lu

u s D u s H *

NC

14

Zygotic mRNAs transcription during slow phase of cellularisation

Lu

u s D s s H *

Maternal clock

24

 

Lu

u u D u u H *

NC

60

 

Lu

u u D u s H *

Maternal clock

27

 
  1. Stars beside the discrete profiles indicate clusters merged into the ZGA cluster.